Recombinant IL-2, Human

• Catalog Number: orb1494709
• Category: Proteins
• Description: Interleukin-2 (IL-2) is a Oglycosylated, four α-helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes.
• Form/Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
• MW: 15~16 kDa, observed by reducing SDS-PAGE.
• Protein Sequence: APTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHL RPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
• Source: CHO
• Biological Activity: ED50 < 2ng/ml, measured in a cell proliferation assay using CTLL-2 cells.
• Endotoxins: < 0.2 EU/μg, determined by LAL method.
• Storage: Lyophilized recombinant Human Interleukin-2 (IL-2) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human Interleukin-2 (IL-2) should be stable up to 1 week at 4°C or up to 2 months at -20°C.
• Buffer/Preservatives: Lyophilized after extensive dialysis against PBS..
• Alternative names: Interleukin-2, IL2
• Note: For research use only
• Application notes: Reconstituted in ddH2O or PBS at 100 μg/ml.
• Expiration Date: 6 months from date of receipt.