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Recombinant IL-15, His, Human
Catalog Number: orb1494833
| Catalog Number | orb1494833 |
|---|---|
| Category | Proteins |
| Description | Interleukin-15 (IL-15) is a cytokine with structural similarity to IL-2. Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15 receptor beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (amongother cells) following infection by virus. This cytokine induces cell proliferation of natural killer cells, which are cells of the innate immune system whose principal role is to kill virally infected cells. IL-15 can stimulate the proliferation of T-lymphocytes. Stimulation by IL-15 occurs following its interaction withIL-15Rα. This interaction may enhance IL-15’s interaction with IL15Rβγc. Recombinant Human IL-15 (His-tag) produced in E.coli is a single non-glycosylated polypeptide chain containing 121 amino acids. A fully biologically active molecule, rhIL-15 (His-tag) has a molecular mass of 13.6 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript. |
| Form/Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| MW | 13.6 kDa, observed by reducing SDS-PAGE. |
| Protein Sequence | MHHHHHHNWV NVISDLKKIE DLIQSMHIDA TLYTESDVHP SCKVTAMKCF LLELQVISLE SGDASIHDTV ENLIILANNS LSSNGNVTES GCKECEELEE KNIKEFLQSF VHIVQMFINT S |
| Source | Escherichia coli. |
| Biological Activity | ED50 2 x 10ˆ6 units/mg. |
| Endotoxins | < 0.2 EU/μg, determined by LAL method. |
| Storage | Lyophilized recombinant Human IL-15(His-tag) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human IL-15(His-tag) should be stable up to 1 week at 4°C or up to 3 months at -20°C. |
| Buffer/Preservatives | Lyophilized after extensive dialysis against PBS. |
| Alternative names | Interleukin-15, IL15 Read more... |
| Note | For research use only |
| Application notes | Reconstituted in ddH2O or PBS at 100 μg/ml. |
| Expiration Date | 6 months from date of receipt. |
Recombinant human IL-15 Protein, Fc & His Tag [orb1550702]
> 95% by SDS-PAGE.
KMP1787, Recombinant human IL-15 Protein is produced by HEK293 Cells expression system. The target protein is expressed with sequence (Asn49-Ser162) of human IL-15 (Accession #NP_000576.1) fused with a Fc, 6×His Tag at the C-terminus.
50 μgRecombinant Human IL15 Protein, His Tag [orb1553496]
≥90% as determined by SDS-PAGE
This protein contains the human IL15(Asn49-Ser162) was fused with the C-terminal His Tag and expressed in E. coli.
100 μg, 50 μgRecombinant human IL-15 Protein, His Tag [orb1551119]
> 95% by SDS-PAGE.
KMP1368, Recombinant human IL-15 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Asn49-Ser162) of human IL-15 (Accession #NP_000576.1) fused with a 6×His Tag at the C-terminus.
100 μg, 50 μgRecombinant human IL-15R alpha/CD215 Protein, Fc & His Tag [orb1551159]
> 95% by SDS-PAGE.
KMP1328, Recombinant human IL-15R alpha/CD215 Protein is produced by HEK293 Cells expression system. The target protein is expressed with sequence (Met1-Thr205) of human IL-15R alpha/CD215 (Accession #NP_002180.1) fused with a Fc, 6×His Tag at the C-terminus.
50 μg
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