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Recombinant Human OSM Protein
Catalog Number: orb527078
| Catalog Number | orb527078 |
|---|---|
| Category | Proteins |
| Description | Oncostatin-M (OSM) is amember of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophagecolony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
| Reactivity | Human |
| Form/Appearance | Lyophilized |
| MW | 22KD |
| UniProt ID | P13725 |
| Protein Sequence | AAIGS CSKEY RVLLG QLQKQ TDLMQ DTSRL LDPYI RIQGL DVPKL REHCR ERPGA FPSEE TLRGL GRRGF LQTLN ATLGC VLHRL ADLEQ RLPKA QDLER SGLNI EDLEK LQMAR PNILG LRNNI YCMAQ LLDNS DTAEP TKAGR GASQP PTPTP ASDAF QRKLE GCRFL HGYHR FMHSV GRVFS KWGES PNRSR |
| Source | E. coli A26-R221 |
| Endotoxins | Less than 1 EU/μg of OSM as determined by LAL method. |
| Storage | Lyophilized recombinant human Oncostatin-M remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, OSM remains stable up to 2 weeks at 4°C or up to 3 months at -20°C. |
| Note | For research use only |
| Expiration Date | 6 months from date of receipt. |
- Item 1 of 1
Human ONCM protein (Active) [orb359147]
> 97% as determined by SDS-PAGE and HPLC.
22.0 kDa
E.Coli
100 μg, 500 μg, 10 μg - Item 1 of 1
Human ONCM protein (Active) [orb359148]
> 97% as determined by SDS-PAGE and HPLC.
23.7 kDa
E.Coli
100 μg, 500 μg, 10 μg - Item 1 of 1
Human ONCM protein (Active) [orb359149]
> 95% as determined by SDS-PAGE and HPLC.
25.8 kDa
E.Coli
10 μg, 100 μg, 500 μg - Item 1 of 1
- Item 1 of 1
Human OSM Protein, His Tag [orb2321371]
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
The protein has a predicted molecular mass of 23.5 kDa after removal of the signal peptide. The apparent molecular mass of OSM-His is approximately 25-35 kDa due to glycosylation.
Mammalian
10 μg, 100 μg, 50 μg
