Recombinant Human Insulin-like Growth Factor-Binding Protein 3

• Catalog Number: orb1906279
• Category: Proteins
• Description: Recombinant Human Insulin-like Growth Factor-Binding Protein 3
• Form/Appearance: Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
• Purity: > 98 % by SDS-PAGE and HPLC analyses.
• MW: Approximately 28.8 kDa, a single non-glycosylated polypeptide chain containing 264 amino acids.
• UniProt ID: P17936
• Protein Sequence: GASSAGLGPV VRCEPCDARA LAQCAPPPAV CAELVREPGC GCCLTCALSE GQPCGIYTER CGSGLRCQPS PDEARPLQAL LDGRGLCVNA SAVSRLRAYL LPAPPAPGNA SESEEDRSAG SVESPSVSST HRVSDPKFHP LHSKIIIIKK GHAKDSQRYK VDYESQSTDT QNFSSESKRE TEYGPCRREM EDTLNHLKFL NVLSPRGVHI PNCDKKGFYK KKQCRPSKGR KRGFCWCVDK YGQPLPGYTT KGKEDVHCYS MQSK
• Source: Escherichia coli
• Expression System: Escherichia coli
• Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by inhibiting IGF-II induced proliferation of serum free human MCF-7 cells is less than 200 ng/ml, corresponding to a specific activity of > 5.0 x103 IU/mg in the presence of 15 ng/ml of rHuIGF-II.
• Endotoxins: Less than 1 EU/ug of rHuIGF-BP3 as determined by LAL method.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Alternative names: Growth-hormone-dependant Binding Protein, IBP-3, I
• Note: For research use only
• Expiration Date: 6 months from date of receipt.