Recombinant Human AIDS (HIV1) antigen

• Catalog Number: orb1678434
• Category: Proteins
• Description: Renin is a highly specific endopeptidase that mediates the cleavage of the circulating substrate angiotensinogen to yield Angiotensin I. Angiotensinconverting enzyme I (ACE) then completes the conversion from Angiotensin I to Angiotensin II which is significant in the regulation of electrolyte balance and blood pressure. Sympathetic stimulation (b1-adrenergic receptors), renal artery hypotension and decreases in sodium delivery to the distal tubules of the kidney signal the release of Renin. The Renin-Angiotensin system (RAS) is essential for regulating blood volume, arterial pressure and normal cardiac and vascular function. Renin is synthesized and secreted by modified smooth muscle cells in the juxtaglomerular apparatus (JGA) of the kidney. Expression of Renin in other tissues, including brain, has been verified although the homeostatic role it may play is yet to be firmly established.
• Species/Host: Mouse
• Tested applications: CLIA, EIA, LF
• Isotype: IgG1 kappa
• Concentration: Lot specific(±20%)
• Form/Appearance: Supplied as a 0.2 μm filtered solution of PBS, pH 7.4
• Purity: > 95% as determined by SDS-PAGE.
• Target: HIV
• UniProt ID: P00797
• Source: E.coli
• Storage: Short term (up to 7 days) store at 2–8°C. Long term, store at -20°C. Avoid multiple freeze/thaw cycles.
• Buffer/Preservatives: PBS, pH 7.4.
• Note: For research use only
• Application notes: Method: sandwich method. Use: Coating. Quality control: Mol Mass: 8.36 kDa AP Mol Mass: 8.50 kDa Purity: ≧90% as determined by reducing SDS-PAGE
• Expiration Date: 6 months from date of receipt.