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Catalog Number | orb1494657 |
---|---|
Category | Proteins |
Description | Adipolean/gArcp30 is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05% of total serum protein. It is an adipocytederived protein with wide ranging paracrine and endocrine effects on metabolism and inflammation. It is induced during adipocyte differentiation, and its secretion is stimulated by insulin. It promotes adipocyte differentiation, fatty acid catabolism, and insulin sensitivity and is negatively correlated with obesity, type 2 diabetes, and atherogenesis. |
Form/Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
MW | 16~17 kDa, observed by reducing SDS-PAGE. |
Protein Sequence | KGEPGEGAYVYRSAFSVGLETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKDVKVSLFKKDK AMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADNDNDSTFTGFLLYHDTN |
Source | HEK 293 |
Biological Activity | ED50 < 2 μg/ml, measured in a cell proliferation assay using M1 cells. |
Endotoxins | < 0.2 EU/μg, determined by LAL method. |
Storage | Lyophilized recombinant Human Adipolean/gArcp30 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human Adipolean/gArcp30 should be stable up to 1 week at 4°C or up to 2 months at -20°C. |
Buffer/Preservatives | Lyophilized after extensive dialysis against PBS. |
Alternative names | Acrp-30, Acrp-30, GBP-28, GBP28, Apm-1 Read more... |
Note | For research use only |
Application notes | Reconstituted in ddH2O or PBS at 100 μg/ml. |
Expiration Date | 6 months from date of receipt. |
> 95% by SDS-PAGE. | |
KMP1758, Recombinant Human Adiponectin/Acrp30/ADIPOQ Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Glu19-Asn244) of human Adiponectin/Acrp30/ADIPOQ (Accession #Q15848) fused with a 6×His Tag at the C-terminus. |
≥90% as determined by SDS-PAGE | |
This protein contains the human Acrp30(Glu19-Asn244) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
> 95% as determined by SDS-PAGE | |
24.8 kDa | |
E. coli |
> 95% as determined by SDS-PAGE | |
24.8 kDa | |
E. coli |
> 95% as determined by SDS-PAGE | |
24.8 kDa | |
E. coli |
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