Rebastinib

• Catalog Number: orb1305227
• Category: Small Molecules
• Description: Rebastinib
• CAS Number: 1020172-07-9
• Purity: 99.84%
• MW: 553.59
• SMILES: CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3cc(nn3-c3ccc4ncccc4c3)C(C)(C)C)c(F)c2)ccn1
• Formula: C₃₀H₂₈FN₇O₃
• Biological Activity: DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC, HCK, FGR, FLT3, KDR, and Tie-2, and low activity to c-Kit. Rebastinib aimed at the Angiopoietin2-Tie2 pathway.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.