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Rat Oncostatin M protein

Rat Oncostatin M protein

Catalog Number: orb107792

DispatchUsually dispatched within 2-3 weeks
$ 340.00
Catalog Numberorb107792
CategoryProteins
DescriptionRecombinant Rat Oncostatin-M (OSM) is a multifunctional cytokine that belongs to the Interleukin-6 subfamily. Among the family members, OSM is most closely related to leukemia inhibitory factor (LIF) and it in fact utilizes the LIF receptor in addition to its specific receptor in the human. A biologically active OSM receptor has been previously described that consists of a heterodimer of leukemia inhibitory factor receptor (LIFR) and gp130. OSM is synthesized by stimulated T-cells and monocytes. Furthermore, the effects of OSM on endothelial cells suggest a pro-inflammatory role for OSM and endothelial cells possess a large number of OSM receptors. Recombinant murine OSM contains 215 amino acids and has a molecular mass of 22.4 kDa. It has approximately 48 % and 72 % amino acid sequence identity with human and murine OSM.
Tested applicationsHPLC, SDS-PAGE
Purity> 96 % by SDS-PAGE and HPLC analyses
ConjugationUnconjugated
MW24.3 kDa
TargetOncostatin M
Protein SequenceKRGCSSSSPK LLSQLKSQAN ITGNTASLLE PYILHQNLNT LTLRAACTEH PVAFPSEDMLRQLSKPDFLS TVHATLGRVW HQLGAFRQQF PKIQDFPELE RARQNIQGIR NNVYCMARLLHPPLEIPEPT QADSGTSRPT TTAPGIFQIK IDSCRFLWGY HRFMGSVGRV FEEWGDGSRRSRRHSPLWAW LKGDHRIRPS RSSQSAMLRS LVPR
Biological OriginE.coli
StorageStore at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Buffer/PreservativesLyophilized from a 0.2 μm filtered concentrated solution in 2xPBS, 1 % Tween-80
Alternative namesRat Oncostatin-M protein
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NoteFor research use only
Expiration Date6 months from date of receipt.
  • Rat Osm protein [orb605273]

    Greater than 85% as determined by SDS-PAGE.

    24.2 kDa

    Mammalian cell

    1 mg, 20 μg, 100 μg
  • Rat Osm protein [orb604977]

    Greater than 85% as determined by SDS-PAGE.

    26.2 kDa

    E.coli

    20 μg, 100 μg, 1 mg
  • Rat Osm protein [orb605499]

    Greater than 85% as determined by SDS-PAGE.

    22.6 kDa

    Yeast

    1 mg, 100 μg, 20 μg
  • Cardiotrophin-1 protein [orb107701]

    HPLC,  SDS-PAGE

    Unconjugated

    10 μg, 100 μg, 500 μg
  • Murine Oncostatin M protein [orb107791]

    HPLC,  SDS-PAGE

    Unconjugated

    > 96 % by SDS-PAGE and HPLC analyses

    20.3 kDa

    10 μg, 100 μg, 500 μg