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Catalog Number | orb107723 |
---|---|
Category | Proteins |
Description | Fibroblast growth factor 21 (FGF-21) encoded by the FGF-21 gene belongs to the large FGF family and it is specifically inducedby HMGCS2 activity. In mice, brown adipose tissue becomes a source of systemic FGF-21 after cold exposure. FGF-21stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (butnot SLC2A4/GLUT4 expression) and the activity depends on the presence of KLB. Recombinant rat FGF-21 contains 180 aminoacids residues and show limited binding to heparin. In addition, rat FGF-21 respectively shows 81 % and 92 % a.a. identity tohuman and murine FGF-21, and it show activity on murine and human cells. |
Tested applications | HPLC, SDS-PAGE |
Purity | > 95 % by SDS-PAGE and HPLC analyses |
Conjugation | Unconjugated |
MW | 19.7 kDa |
Target | FGF-21 |
Protein Sequence | AYPISDSSPL LQFGGQVRQR YLYTDDDQDT EAHLEIREDG TVVGTAHRSPESLLELKALK PGVIQILGVK ASRFLCQQPD GTLYGSPHFD PEACSFRELLLKDGYNVYQS EAHGLPLRLP QKDSQDPATR GPVRFLPMPG LPHEPQEQPGVLPPEPPDVG SSDPLSMVEP LQGRSPSYAS |
Biological Origin | E.coli |
Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
Buffer/Preservatives | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, 500 mM NaCl, pH 7.4 |
Alternative names | Rat Fibroblast Growth Factor-21 protein Read more... |
Note | For research use only |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Rat FGF-21 protein
HPLC, SDS-PAGE | |
Unconjugated | |
> 97% by SDS-PAGE and HPLC analyses | |
19.9 kDa |
ELISA, WB | |
Greater than 95% as determined by SDS-PAGE | |
19.7 kDa | |
E.Coli |
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