RAS activator compound 1

• Catalog Number: orb746410
• Category: Small Molecules
• Description: RAS activator compound 1 is a small molecule RAS activator compound that increases the rate of SOS-catalyzed nucleotide exchange in vitro with EC50 of 14 uM; targets SOS1 induced biphasic modulation of RAS-GTP and ERK phosphorylation levels, through negative feedback on SOS1 that regulates the interaction between SOS1 and GRB2.
• CAS Number: [1579978-17-8]
• Purity: > 98%
• MW: 449.983
• SMILES: C(NC1CCN(CC2C3=C(NC=2)C=CC(Cl)=C3)CC1)(=O)[C@H](N)CC1C2=C(NC=1)C=CC=C2
• Formula: C₂₅H₂₈ClN₅O
• Storage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical Structure: 1579978-17-8