Randox - Mitochondrial Glycerol-3-Phosphate Dehydrogenase (mGPD)

• Catalog Number: RCP9303
• Category: Proteins
• Description: Mitochondrial glycerol-3-phosphate dehydrogenase (mGPD) is a Ca2+ -sensitive, FAD-binding protein, located on the outer surface of the inner mitochondrial membrane. mGPD catalyses the oxidation of glycerol-3-phosphate to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Two isoforms have been described for mGPD. Isoform 1 comprises 727aa residues, whereas isoform 2 lacks 126aa residues of the N-terminus. Deficiency of mGPD appears to contribute to the impairment of glucose-stimulated insulin release in several animal models of non-insulin dependent diabetes mellitus.
• Tag: N terminal containing a HIS tag
• Form/Appearance: Liquid
• Purity: > 95 %, by SDS-PAGE under reducing conditions
• MW: 66.26 kDa
• UniProt ID: P43304
• Protein Length: Ala43-Tyr600
• Source: E.coli -derived human recombinant protein
• Expression System: E.coli
• Storage: at -20 °C
• Buffer/Preservatives: 20 mM Tris HCl pH 8, 1 mM EDTA, 50% Glycerol
• Alternative names: Glycerol-3-Phosphate Dehydrogenase 2, GPD2, Glycer
• Note: For research use only
• Application notes: ELISA, Western Blotting, etc.
• Expiration Date: 6 months from date of receipt.