Randox - Matrix Metalloproteinase-9 (MMP-9)

• Catalog Number: RCP9311
• Category: Proteins
• Description: Matrix metalloproteinases are a family of zinc and calciumdependent endopeptidases, which degrade extracellular matrix proteins. MMP-9 is secreted as a 92kDa zymogen. Cleavage of pro-MMP-9 results in the active enzyme with a molecular weight of ~82kDa. MMP-9 has a gelatinbinding domain consisting of three fibronectin type II units, a catalytic domain containing the zinc-binding site, a proline-rich type V collagen-homologous domain and a hemopexin-like domain. MMP9 is produced by monocytes, macrophages, neutrophils, keratinocytes, fibroblasts, osteoclasts and endothelial cells, and is involved in inflammatory responses, tissue remodelling, wound healing, tumour growth and metastasis.
• Tag: N terminal containing a HIS tag
• Form/Appearance: Liquid
• Purity: > 95 %, by SDS-PAGE under reducing conditions
• MW: 42.03 kDa
• UniProt ID: P14780
• Protein Length: Asp113- Glu450
• Source: E.coli -derived human recombinant protein
• Expression System: E.coli
• Storage: at -20 °C
• Buffer/Preservatives: 20 mM Tris HCl pH 8, 50% Glycerol
• Alternative names: Matrix metalloproteinase 9, gelatinase B, CLG4B, G
• Note: For research use only
• Application notes: ELISA, Western Blotting, etc.
• Expiration Date: 6 months from date of receipt.