Randox - Glutathione S-Transferase Omega 1 140 D (GST-01)

• Catalog Number: RCP9196
• Category: Proteins
• Description: GSTO1 is a member of the theta class glutathione Stransferase-like (GSTTL) protein family. GSTO1 is expressed in a wide range of human tissues and exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities and also catalyzes the reduction of monomethylarsonate, an intermediate in the pathway of arsenic biotransformation. GSTO1 protects from oxidative stress, a risk factor for Alzheimer disease, vascular dementia and stroke. Several polymorphisms in the coding regions of the human GSTO1 have been identified. A polymorphism causing an alanine-toaspartate (A140D) substitution in amino acid 140 produces a variant with lowered enzyme activities in the arsenic biotransformation.
• Tag: N terminal containing a HIS tag
• Form/Appearance: Liquid
• Purity: > 95 %, by SDS-PAGE under reducing conditions
• MW: 32.11 kDa
• UniProt ID: P78417
• Protein Length: Met1- Leu241
• Source: E.coli -derived human recombinant protein
• Expression System: E.coli
• Storage: at -20 °C
• Buffer/Preservatives: 20 mM Tris-HCl pH 8.0, 50 % Glycerol
• Alternative names: GSTTLp28; P28, glutathione S-transferase omega 1-1
• Note: For research use only
• Application notes: ELISA, Western Blotting, etc.
• Expiration Date: 6 months from date of receipt.