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Ralimetinib
Catalog Number: orb1706734
| Catalog Number | orb1706734 |
|---|---|
| Category | Small Molecules |
| Description | Ralimetinib |
| CAS Number | 862505-00-8 |
| Purity | 98% |
| MW | 420.53 |
| SMILES | C(C)(C)(C)C=1NC(=C(N1)C2=CC=C(F)C=C2)C=3N=C4N(CC(C)(C)C)C(N)=NC4=CC3 |
| Formula | C24H29FN6 |
| Biological Activity | Ralimetinib selectively inhibits phosphorylation of MK2 (Thr334) and has no effect on phosphorylation of p38α MAPK, JNK, ERK1/2, c-Jun, ATF2, or c-Myc. Ralimetinib is an effective and selective, ATP-competitive inhibitor of p38 MAPK α/β (IC50s: 5.3 and 3.2 nM, respectively). |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Ralimetinib 2MsOH(LY2228820) [orb341560]
[862507-23-1]
612.7364
C26H37FN6O6S2
10 mM * 1 mL in DMSO, 1 g, 100 mg, 250 mgRalimetinib dimesylate [orb1301121]
99.38%
862507-23-1
612.74
C26H37FN6O6S2
100 mg, 5 mg, 1 mL*10mM (in DMSO), 50 mg, 25 mg, 10 mg, 1 mgRalimetinib dimesylate [Out of stock] [orb1086862]
862507-23-1
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