(Rac)-Lonafarnib

• Catalog Number: orb1744722
• Category: Small Molecules
• Description: (Rac)-Lonafarnib
• CAS Number: 193275-86-4
• MW: 638.82
• SMILES: BrC1=C2C(C=3C(CCC2=CC(Cl)=C1)=CC(Br)=CN3)C4CCN(C(CC5CCN(C(N)=O)CC5)=O)CC4
• Formula: C₂₇H₃₁Br₂ClN₄O₂
• Biological Activity: (Rac)-Lonafarnib (Sch66336 racemate) is the racemic form of the potent, orally active farnesyl transferase (FTase) inhibitor, Lonafarnib. It effectively inhibits H-ras, K-ras, and N-ras with IC50 values of 1.9 nM, 5.2 nM, and 2.8 nM, respectively. Additionally, Lonafarnib exhibits activities against the hepatitis delta virus (HDV).
• Note: For research use only
• Expiration Date: 12 months from date of receipt.