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Catalog Number | orb1691997 |
---|---|
Category | Small Molecules |
Description | (Rac)-Finerenone |
CAS Number | 1050477-27-4 |
Purity | 98% |
MW | 378.432 |
SMILES | CCOc1ncc(C)c2NC(C)=C(C(c3ccc(cc3OC)C#N)c12)C(N)=O |c:11| |
Formula | C21H22N4O3 |
Biological Activity | Rac-Finerenone, also known as (Rac)-BAY 94-8862, is the racemate derivative of Finerenone, a selective third-generation nonsteroidal mineralocorticoid receptor antagonist (MR) that is taken orally. With an IC50 value of 18 nM, Finerenone exhibits exceptional selectivity against the glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |