RA-9

• Catalog Number: orb746539
• Category: Small Molecules
• Description: RA-9 is a potent and selective proteasome-associated deubiquitinating enzymes (DUBs) inhibitor with favorable toxicity profile and anticancer activity. RA-9 blocks ubiquitin-dependent protein degradation without impacting 20S proteasome proteolytic activity. RA-9 selectively induces onset of apoptosis in ovarian cancer cell lines and primary cultures derived from donors. RA-9 induces endoplasmic reticulum (ER)-stress responses in ovarian cancer cells[1].
• CAS Number: [919091-63-7]
• MW: 365.3395045
• SMILES: C(/C1C=CC([N+](=O)[O-])=CC=1)=C1/CNC/C(=C\C2C=CC([N+](=O)[O-])=CC=2)/C/1=O
• Formula: C₁₉H₁₅N₃O₅
• Note: For research use only
• Expiration Date: 12 months from date of receipt.