(R)-(-)-Gossypol acetic acid

• Catalog Number: orb1300804
• Category: Small Molecules
• Description: (R)-(-)-Gossypol acetic acid
• CAS Number: 866541-93-7
• Purity: 96.73%
• MW: 578.61
• SMILES: CC(O)=O.CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O
• Formula: C₃₂H₃₄O₁₀
• Biological Activity: (R)-(-)-Gossypol acetic acid (AT101 acetate) , the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM; does not inhibit BIR3 domain and BID. Phase 2.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.