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Catalog Number | orb2278784 |
---|---|
Category | Small Molecules |
Description | (R)-Elexacaftor |
CAS Number | 2229860-99-3 |
MW | 597.65 |
SMILES | C(NS(=O)(=O)C1=CN(C)N=C1C)(=O)C2=C(N=C(C=C2)N3N=C(OCC(C(F)(F)F)(C)C)C=C3)N4C[C@H](C)CC4(C)C |
Formula | C26H34F3N7O4S |
Biological Activity | (R)-Elexacaftor, an enantiomer of Elexacaftor, functions as a modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It exhibits an EC50 of 0.29 µM for the CFTR dF508 mutation [1]. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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