(R)-Bambuterol

• Catalog Number: orb1740785
• Category: Small Molecules
• Description: (R)-Bambuterol
• CAS Number: 788821-30-7
• Purity: 0.98
• MW: 367.44
• SMILES: [C@@H](CNC(C)(C)C)(O)C1=CC(OC(N(C)C)=O)=CC(OC(N(C)C)=O)=C1
• Formula: C₁₈H₂₉N₃O₅
• Biological Activity: Bambuterol is a prodrug of β2-agonist commonly used for the treatment of asthma and chronic obstructive pulmonary disease (COPD) with the advantage of once daily dosing and favorable side effect profile. Administration of a single-dose of R-bambuterol resulted in dose-dependent reductions in the levels of plasma LDL-C, high-density lipoprotein cholesterol (HDL-C), total cholesterol (TC), apolipoprotein B (ApoB) and apolipoprotein A1 (ApoA1) at Tmax. R-bambuterol can lower the plasma levels of LDL-C, and marginally raise the ratio of ApoA1/ApoB (indicator of HDL-C/LDL-C) with both a single dose and multiple doses. R-bambuterol was more potent in LDL-C lowering than rac-bambutero
• Note: For research use only
• Expiration Date: 12 months from date of receipt.