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Catalog Number | orb611811 |
---|---|
Category | Small Molecules |
Description | Quizartinib (AC220) is a potent, selective, second-generation FLT3 inhibitor with Kd of 1.6 nM, inhibits Wt FLT3 and FLT3-ITD autophosphorylation in MV4-11cell with IC50 of 4.2 and 1.1 nM, respectively. |
CAS Number | [1132827-21-4] |
MW | 633.589 |
SMILES | Cl.Cl.O=C(NC1=CC=C(C=C1)C2=CN3C(=N2)SC4=C3C=CC(OCCN5CCOCC5)=C4)NC6C=C(ON=6)C(C)(C)C |
Formula | C29H34Cl2N6O4S |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |