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Catalog Number | orb154726 |
---|---|
Category | Small Molecules |
Description | Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Phase 1/2. |
CAS Number | [950769-58-1] |
MW | 560.673 |
SMILES | N(C1C=C(C(C)(C)C)ON=1)C(NC1=CC=C(C2=CN3C4=CC=C(OCCN5CCOCC5)C=C4SC3=N2)C=C1)=O |
Formula | C29H32N6O4S |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Chemical structure of Quizartinib (AC220)