Pyr10

• Catalog Number: orb611723
• Category: Small Molecules
• Description: Pyr10 is a pyrazole derivative and a selective TRP cation 3 (TRPC3) inhibitor. Pyr10 inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells with an IC50 of 0.72 μM (IC50 of 13.08 μM for store operated Ca2+ entry in BRL-2H3 cells). Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels[1].
• CAS Number: [1315323-00-2]
• MW: 449.3701
• SMILES: O=S(=O)(NC1C=CC(N2C(C(F)(F)F)=CC(C(F)(F)F)=N2)=CC=1)C1C=CC(C)=CC=1
• Formula: C₁₈H₁₃F₆N₃O₂S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.