[Pyr1]-Apelin 13

• Catalog Number: orb1140672
• Category: Proteins
• Description: Endogenous agonist for the apelin APJ receptor; Peptides.
• CAS Number: 217082-60-5
• Modifications: X is pGlu.
• Structure: Glp-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
• Target Areas: Apelin receptors
• Form/Appearance: Freeze dried solid
• Purity: > 95% by HPLC
• MW: 1533.8 Da
• Formula: C₆₉H₁₀₉N₂₂O₁₆S
• Solubility (25°C): Soluble in dilute acid and physiological buffers
• Protein Sequence: XRPRLSHKGPMPF
• Storage: Store dry, frozen and in the dark
• Alternative names: [pGlu1]-apelin-13, [pGlu1]-apelin-13 , 217082-60-5
• Background: [Pyr1]-Apelin 13 or [pGlu1]-apelin-13 is a highly potent pyroglutamyl form of apelin 13 which acts as the endogenous ligand for the apelin APJ receptor, with an EC50 of 0.37 nM. [Pyr1]-Apelin 13 is the predominant isoform detected in human heart and plasma and acts as a potent inotropic agent and vasodilator.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.