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Catalog Number | orb131867 |
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Category | Antibodies |
Description | Rabbit polyclonal to PTPN3. Tyrosine-protein phosphatase non-receptor type 3 (PTPN3) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN3 contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of PTPN3. PTPN3 was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for PTPN3. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human |
Immunogen | C-terminal region of human PTPN3 |
Concentration | 100 μg/ml BSA |
Dilution range | WB:1:1000-1:3000 |
Purity | Affinity purification |
Conjugation | Unconjugated |
MW | 104 |
UniProt ID | P26045 |
Storage | -20°C |
Buffer/Preservatives | 0.01% NaN3 |
Alternative names | anti Tyrosine-protein phosphatase non-receptor typ Read more... |
Note | For research use only |
Application notes | < strong>WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications. < br>< strong>Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human PTPN3. |
Expiration Date | 12 months from date of receipt. |