PS210

• Catalog Number: orb1307839
• Category: Small Molecules
• Description: PS210
• CAS Number: 1221962-86-2
• Purity: 99.65%
• MW: 380.31
• SMILES: C(C(C(O)=O)C(O)=O)(CC(=O)C1=CC=C(C(F)(F)F)C=C1)C2=CC=CC=C2
• Formula: C₁₉H₁₅F₃O₅
• Biological Activity: PS210 is a potent and selective activator of PDK1 (Kd: 3 μM), specifically targeting the PIF-binding pocket of PDK1, without acting against other protein kinases such as S6K, PKB/Akt, or GSK3. Its prodrug, PS423, serves as a substrate-selective inhibitor of PDK1 in cells, inhibiting the phosphorylation and activation of S6K.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.