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Catalog Number | orb1307856 |
---|---|
Category | Small Molecules |
Description | Praliciguat |
CAS Number | 1628730-49-3 |
Purity | 99.05% |
MW | 534.36 |
SMILES | C(N1C(=CC(=N1)C=2N=C(NCC(C(F)(F)F)(C(F)(F)F)O)C(F)=CN2)C=3C=CON3)C4=C(F)C=CC=C4 |
Formula | C21H14F8N6O2 |
Biological Activity | Praliciguat (IW-1973) stimulates sGC in HEK-293 cells (EC50: 197 nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator. It also enhances NO signaling and acts as a vasodilator. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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