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PPARδ agonist 9

SKU: orb2278393

Description

PPARδ agonist 9 (compound 21), with an EC50 of 3.6 nM, effectively decreases serum MCP-1 concentrations in mice and significantly reduces atherosclerotic development in the LDLr-KO model with a 50-60% inhibition rate in vivo.

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Key Properties

CAS Number928023-21-6
MW569.04
FormulaC26H28ClF3N4O3S
SMILESC(COC1=CC(CC(O)=O)=CC(Cl)=C1)C2(CCN(CC2)C=3SC=4C(N3)=CC=C(C(F)(F)F)N4)N5CCCC5
TargetPPAR

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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PPARδ agonist 9 (orb2278393)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

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