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Catalog Number | orb1704215 |
---|---|
Category | Small Molecules |
Description | Posaconazole hydrate |
CAS Number | 1198769-38-8 |
Purity | 98% |
MW | 718.79 |
SMILES | C([C@@]1(C[C@H](COC2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)N5C(=O)N([C@H]([C@H](C)O)CC)N=C5)CO1)C6=C(F)C=C(F)C=C6)N7C=NC=N7.O |
Formula | C37H44F2N8O5 |
Biological Activity | Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. Posaconazole is a sterol C14ɑ demethylase inhibitor (IC50: 0.25 nM). Posaconazole strongly inhibits 14-alpha demethylase, a cytochrome P450-dependent enzyme. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |