Ponatinib Hydrochloride

• Catalog Number: orb1703739
• Category: Small Molecules
• Description: Ponatinib Hydrochloride
• CAS Number: 1114544-31-8
• Purity: 100%
• MW: 569.02
• SMILES: Cl.CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cnc4cccnn34)cc2C(F)(F)F)CC1
• Formula: C₂₉H₂₈ClF₃N₆O
• Biological Activity: Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.