Ponatinib Hydrochloride

• Catalog Number: orb1703739
• Category: Small Molecules
• Description: Ponatinib Hydrochloride
• CAS Number: 1114544-31-8
• Purity: 100%
• MW: 569.02
• SMILES: Cl.O=C(NC1=CC=C(C(=C1)C(F)(F)F)CN2CCN(C)CC2)C3=CC=C(C(C#CC4=CN=C5C=CC=NN45)=C3)C
• Formula: C₂₉H₂₈ClF₃N₆O
• Biological Activity: Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.