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Catalog Number | orb1306413 |
---|---|
Category | Small Molecules |
Description | Polmacoxib |
CAS Number | 301692-76-2 |
Purity | 98.49% |
MW | 361.39 |
SMILES | CC1(C)OC(=C(C1=O)c1cccc(F)c1)c1ccc(cc1)S(N)(=O)=O |
Formula | C18H16FNO4S |
Biological Activity | Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
301692-76-2 | |
361.4 | |
C12H16FNO4S |