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Catalog Number | orb1306413 |
---|---|
Category | Small Molecules |
Description | Polmacoxib |
CAS Number | 301692-76-2 |
Purity | 98.49% |
MW | 361.39 |
SMILES | O=C1C(=C(OC1(C)C)C2=CC=C(S(N)(=O)=O)C=C2)C3=CC(F)=CC=C3 |
Formula | C18H16FNO4S |
Biological Activity | Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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