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Catalog Number | orb699653 |
---|---|
Category | Antibodies |
Description | Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology. |
Species/Host | Mouse |
Clonality | Recombinant |
Clone Number | rPODXL/2184 |
Tested applications | ELISA |
Reactivity | Human |
Isotype | Mouse IgG1, kappa |
Immunogen | A portion of amino acids 310-447 from the human protein was used as the immunogen for the recombinant Podocalyxin antibody. |
Dilution range | ELISA: order Ab without BSA for coating |
Purity | Protein G affinity chromatography |
Conjugation | Unconjugated |
Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
Hazard Information | This recombinant Podocalyxin antibody is available for research use only. |
UniProt ID | O00592 |
Storage | Store the recombinant Podocalyxin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide). |
Buffer/Preservatives | 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced), 0.05% sodium azide |
Note | For research use only |
Application notes | Optimal dilution of the recombinant Podocalyxin antibody should be determined by the researcher. |
Expiration Date | 12 months from date of receipt. |
SDS-PAGE analysis of purified, BSA-free recombinant Podocalyxin antibody (clone rPODXL/2184) as confirmation of integrity and purity.
FACS, IF, IHC-P, WB | |
Human, Rat | |
Mouse | |
Monoclonal | |
Unconjugated |
IHC-P, WB | |
Human, Rat | |
Mouse | |
Monoclonal | |
Unconjugated |
FACS, IF, IHC-P | |
Human, Rat | |
Mouse | |
Monoclonal | |
Unconjugated |
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