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Catalog Number | orb1708839 |
---|---|
Category | Small Molecules |
Description | Plecanatide acetate |
CAS Number | 1075732-84-1 |
Purity | 98% |
MW | 1741.94 |
SMILES | CC(O)=O.[H][C@@]1(CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@]([H])(CSSC[C@]2([H])NC(=O)[C@H](C)NC(=O)C(NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@]([H])(CSSC[C@H](NC(=O)CNC(=O)[C@@]([H])(NC2=O)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(O)=O)NC1=O)C(C)C)C(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CC(N)=O |@:93| |
Formula | C67H108N18O28S4 |
Biological Activity | Plecanatide acetate is a agonist of guanylate cyclase-C (GC-C) receptor( EC50 of 190 nM in T84 cells), and shows anti-inflammatory activity in models of murine colitis. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |