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Catalog Number | orb1305236 |
---|---|
Category | Small Molecules |
Description | Pitstop 2 |
CAS Number | 1419320-73-2 |
Purity | 100% |
MW | 473.36 |
SMILES | Brc1ccc(\C=C2/SC(NS(=O)(=O)c3cccc4ccccc34)=NC2=O)cc1 |
Formula | C20H13BrN2O3S2 |
Biological Activity | Pitstop2 is a selective inhibitor of amphiphysin association of clathrin terminal domain with an IC50 value of 12 μM. Pitstop2 acutely interferes with receptor-mediated endocytosis, entry of HIV, and synaptic vesicle recycling. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
1419320-73-2 |
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