PIAS3 (C) Antibody, Rabbit Polyclonal

• Catalog Number: orb66717
• Category: Antibodies
• Description: Rabbit polyclonal to PIAS3.Protein inhibitor of activated STAT3 (PIAS3) is a member of the PIAS proteins. The mammalian PIASfamily is composed of four proteins: PIAS1, PIAS2 (PIASx), PIAS3, and PIAS4 (PIASy). PIAS proteinsfunction as E3 small ubiquitin-like modifier (SUMO) ligases, which facilitate the conjugation of SUMOto the specific protein substrates. PIAS3 has been shown to play important roles in the transcriptionalregulation of various cellular pathways, including STAT, SMAD and the steroid hormone signalingpathways. The effects of this transcriptional co-regulation, transactivation or silencing, may varydepending upon the biological context.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human, Mouse
• Immunogen: C-terminal region of mouse PIAS3
• Dilution range: WB:1:1000-1:5000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 68
• UniProt ID: O88907
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-PIAS3 antibody,anti-Protein inhibitor of acti
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human HepG2 cells using PIAS3 antibody