You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb1909002 |
---|---|
Category | Small Molecules |
Description | PI-103 Hydrochloride |
CAS Number | 371935-79-4 |
MW | 384.82 |
SMILES | Cl.OC1=CC=CC(=C1)C2=NC3=C(OC4=NC=CC=C43)C(=N2)N5CCOCC5 |
Formula | C19H17ClN4O3 |
Biological Activity | PI-103 Hydrochloride is a potent dual inhibitor of PI3K and mTOR, demonstrating inhibitory IC50 values of 8 nM for p110α, 88 nM for p110β, 48 nM for p110δ, 150 nM for p110γ, 20 nM for mTORC1, and 83 nM for mTORC2, respectively. Additionally, it inhibits DNA-PK with an IC50 of 2 nM and induces autophagy [1] [2] [3] [4]. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Filter by Rating