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Catalog Number | orb1733006 |
---|---|
Category | Antibodies |
Description | Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6. |
Species/Host | Rabbit |
Clonality | Monoclonal |
Tested applications | IHC, WB |
Reactivity | Human, Mouse, Rat |
Isotype | Rabbit IgG |
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser181 of human TAOK1 |
Concentration | 1mg/ml |
Dilution range | WB: 1/500-1/1000; IHC: 1/50-1/100 |
Conjugation | Unconjugated |
MW | Calculated MW: 116 kDa; Observed MW: 105,116,138 kDa |
Entrez | 57551, 51347, 9344 |
UniProt ID | Q9UL54, Q9H2K8, Q7L7X3 |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Buffer/Preservatives | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin |
Alternative names | DPK; JIK; hKFC-A; MAP3K18 Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
IHC-P, WB | |
Human, Mouse, Rat | |
Rabbit | |
Monoclonal | |
Unconjugated |
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