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Catalog Number | orb1300855 |
---|---|
Category | Small Molecules |
Description | PHA-680632 |
CAS Number | 398493-79-3 |
Purity | 99.03% |
MW | 501.62 |
SMILES | N(C(=O)C1=CC=C(C=C1)N2CCN(C)CC2)C=3C4=C(CN(C(NC5=C(CC)C=CC=C5CC)=O)C4)NN3 |
Formula | C28H35N7O2 |
Biological Activity | PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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