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Catalog Number | orb746324 |
---|---|
Category | Small Molecules |
Description | PF00835231(SARS-CoV-2 inhibitor 5h) is areversible-covalent inhibitor of SARS-CoV-2 main protease (Mpro) with EC50 of 4.2 μM. Compound 5h blocks the infectivity and cytopathicity of the virus with high potency and without any detectable cytotoxicity even at 200?μM.PF-00835231 is a potent inhibitor of CoV-2 3CLpro with IC50 of 4 nM and shows suitable pharmaceutical properties to warrant further development as an intravenous treatment for COVID-19. |
CAS Number | [870153-29-0] |
MW | 575.68 |
SMILES | COc1c2c([nH]c(c2)C(N[C@H](C(N[C@H](C(c2sc3c(cccc3)n2)=O)C[C@H]2C(=O)NCC2)=O)CC(C)C)=O)ccc1 |
Formula | C30H33N5O5S |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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