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PF-5274857
Catalog Number: orb573014
| Catalog Number | orb573014 |
|---|---|
| Category | Small Molecules |
| Description | PF-5274857 is a potent and selective Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 and Ki of 5.8 nM and 4.6 nM, respectively, and can penetrate the blood–brain barrier. |
| CAS Number | [1373615-35-0] |
| MW | 436.96 |
| SMILES | O=C(N1CCN(C2=NC=C(Cl)C(C3=NC=C(C)C=C3C)=C2)CC1)CCS(=O)(C)=O |
| Formula | C20H25ClN4O3S |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
PF-5274857 [orb1301768]
98.53%
1373615-35-0
436.96
C20H25ClN4O3S
1 ml x 10 mm (in DMSO), 2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg
