PF-06807656

SKU: orb1987143

Description

PF-06807656 is insensitive to the introduction of the N171D mutation in the ROMK conduction pore that greatly diminishes the activity of other small-molecule inhibitors. PF-06807656 is an effective ROMK inhibitor (Tl+ flux IC50 = 160 nM).

Key Properties

• MW: 449.91
• Formula: C₁₉H₂₀ClN₅O₄S
• SMILES: O=C(NC(C1=NN(C)N=C1)C)C2=CC(S(=O)(NC3=CC=C(Cl)C=C3)=O)=C(OC)C=C2
• Target: Others

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

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