PF-06424439 methanesulfonate

• Catalog Number: orb1309264
• Category: Small Molecules
• Description: PF-06424439 methanesulfonate
• CAS Number: 1469284-79-4
• Purity: 99.79%
• MW: 536.05
• SMILES: O=C([C@H]1CN(C2=CC=C3C(NC(C4(N5N=CC(Cl)=C5)CC4)=N3)=N2)CCC1)N6CCCC6.CS(=O)(O)=O
• Formula: C₂₃H₃₀ClN₇O₄S
• Biological Activity: PF-06424439 methanesulfonate, an orally administered, potent, and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM, demonstrates slow reversibility and time-dependent inhibition. It operates in a noncompetitive manner relative to the acyl-CoA substrate, marking its efficacy in targeting DGAT2.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.