PF-05221304(Clesacostat)

• Catalog Number: orb1089394
• Category: Small Molecules
• Description: PF-05221304 is an orally bioavailable, liver-directed and dual ACC1 (and ACC2) inhibitor with IC50s of 7.5 nM for rat ACC1, 8.2 nM for rat ACC2, 12.4 nM for human ACC1 and 8.7 nM for human ACC2. PF-05221304 is a substrate for organic anion transport polyp
• CAS Number: [1370448-25-1]
• MW: 502.56
• SMILES: O=C(O)C1=CC=C(C2=NC(OC)=CC(C(N3CCC(C4)(CC3)CC5=C(N(C(C)C)N=C5)C4=O)=O)=C2)C=C1
• Formula: C₂₈H₃₀N₄O₅
• Note: For research use only
• Expiration Date: 12 months from date of receipt.