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Catalog Number | orb1299763 |
---|---|
Category | Small Molecules |
Description | PF 05089771 |
CAS Number | 1235403-62-9 |
Purity | 99.42% |
MW | 500.35 |
SMILES | O(C1=C(C=C(Cl)C=C1)C=2C(N)=NNC2)C3=C(Cl)C=C(S(NC4=CSC=N4)(=O)=O)C(F)=C3 |
Formula | C18H12Cl2FN5O3S2 |
Biological Activity | PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV. It shows a slow onset of the block that is depolarization and concentration-dependent. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
[1235403-62-9] | |
500.35 | |
C18H12Cl2FN6O3S2 |
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