Pexmetinib(ARRY-614)

• Catalog Number: orb654669
• Category: Small Molecules
• Description: Pexmetinib is a potent Tie-2 and p38 MAPK dual inhibitor, with IC50s of 1 nM, 35 nM and 26 nM for Tie-2, p38α and p38β, respectively, and can be used in the research of acute myeloid leukemia.
• CAS Number: [945614-12-0]
• MW: 556.25
• SMILES: O=C(NCC1=CC(F)=CC=C1OC2=CC3=C(N(CCO)N=C3)C=C2)NC4=CC(C(C)(C)C)=NN4C5=CC=C(C)C=C5
• Formula: C₃₁H₃₃FN₆O₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.