Pevonedistat

• Catalog Number: orb1300861
• Category: Small Molecules
• Description: Pevonedistat
• CAS Number: 905579-51-3
• Purity: 99.20%
• MW: 443.52
• SMILES: N(C1=C2C(N(C=C2)[C@@H]3C[C@@H](COS(N)(=O)=O)[C@@H](O)C3)=NC=N1)[C@@H]4C=5C(CC4)=CC=CC5
• Formula: C₂₁H₂₅N₅O₄S
• Biological Activity: Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM). Pevonedistat can be used for the treatment of myelodysplastic syndromes (MDS) and also has antitumor activity.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.