Penciclovir

• Catalog Number: orb1307915
• Category: Small Molecules
• Description: Penciclovir
• CAS Number: 39809-25-1
• Purity: 99.10%
• MW: 253.26
• SMILES: C(CC(CO)CO)N1C2=C(N=C1)C(=O)N=C(N)N2
• Formula: C₁₀H₁₅N₅O₃
• Biological Activity: Penciclovir (BRL 39123) is a Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. In HSV infected cells, penciclovir is phosphorylated by viral thymidine kinase and subsequently converted by cellular kinases into the active metabolite, penciclovir triphosphate, which competitively inhibits viral HSV polymerase by blocking deoxyguanosine triphosphate substrate binding. As a result, herpes viral DNA synthesis and replication are selectively inhibited.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.