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Catalog Number | orb1685258 |
---|---|
Category | Small Molecules |
Description | PD-1/PD-L1-IN-9 |
CAS Number | 2628506-54-5 |
Purity | 99.37% |
MW | 348.44 |
SMILES | CC1=C(C=2N=C(OC)C(CNCCO)=CC2)C=CC=C1C3=CC=CC=C3 |
Formula | C22H24N2O2 |
Biological Activity | PD-1/PD-L1-IN-9, with an IC50 of 3.8 nM, is a potent and orally active inhibitor of the PD-1/PD-L1 interaction. It enhances the immune cells' ability to kill tumor cells and demonstrates significant antitumor activity in vivo in a CT26 mouse model. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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