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Catalog Number | orb1744749 |
---|---|
Category | Small Molecules |
Description | PD-1/PD-L1-IN-23 |
CAS Number | 2597056-04-5 |
MW | 703.41 |
SMILES | O(CC1=CC=2C(C=C1)=NON2)C3=C(CN[C@@H](C(OCC)=O)CO)C=C(Cl)C(OCC4=C(Br)C(=CC=C4)C5=CC=CC=C5)=C3.Cl |
Formula | C32H30BrCl2N3O6 |
Biological Activity | PD-1/PD-L1-IN-23 is a potent, orally active ester prodrug of L7, a benzooxadiazole derivative, and functions as an inhibitor of PD-1/PD-L1. It has been biologically evaluated for its inhibitory effects on PD-L1, demonstrating significant antitumor effects in both syngeneic tumor models and PD-L1 humanized mice. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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