PD-1/PD-L1-IN-23

• Catalog Number: orb1473040
• Category: Small Molecules
• Description: PD-1/PD-L1-IN-23 is a potent and orally active inhibitor of PD-1/PD-L1. PD-1/PD-L1-IN-23 is an ester prodrug of L7. L7 is a benzo[c][1,2,5]oxadiazole derivative and biologically evaluated as inhibitors of PD-L1. PD-1/PD-L1-IN-23 displays significant antitumor effects in tumor models of syngeneic and PD-L1 humanized mice.
• CAS Number: [2597056-04-5]
• MW: 703.41
• SMILES: ClC1=CC(CN[C@@H](C(OCC)=O)CO)=C(OCC2=CC3=NON=C3C=C2)C=C1OCC4=C(Br)C(C5=CC=CC=C5)=CC=C4.[H]Cl
• Formula: C₃₂H₃₁ClFN₃O₅
• Note: For research use only
• Expiration Date: 12 months from date of receipt.